Veronica Ghini

Senior Post Doc Researcher

 Foto VG

AFFILIATION:
CERM and Department of Chemistry

ADDRESS:
Via L. Sacconi 6
50019 Sesto Fiorentino, (FI) -Italy

CONTACTS:
Tel: +39 055 4574266
e-mail: ghini[at]cerm.unifi.it - veronica.ghini[at]unifi.it

RESEARCH PROFILES:
ORCID_ID profile
Google scholar profile
Scopus profile

Veronica Ghini was born in 1989. She graduated with laude in Molecular Biotechnology at the University of Florence and in 2016 she obtained the title of PhD in "Structural Biology" presenting a thesis focused on the applications of Metabolomics using NMR spectroscopy in biomedicine. Currently, she is a senior post-doc at the Department of Chemistry of the University of Florence. Her main research field deals with the application of NMR spectroscopy to study biological matrices with a special focus on metabolomics. 
She has been the recipient of a Veronesi Foundation Post-doctoral Fellowship (2018) and a AIRC Post-doctoral Fellowship (2019-2020) as well as of a short term EMBO fellowship (2016). For her research activities she was awarded with 3 prizes: i) GIDRM under 35 Award (2022); ii) Galileo Galilei Giovani for Chemical Sciences (2022); iii) Lisa de Conciliis Award (2021). She actively promoted the application of NMR in biological sciences in various scientific communities by participating in several national and international congresses. She is Co-Editor for the volume “Metabolomics and Its Impact on Health and Diseases” of the series Handbook of Experimental Pharmacology, Springer Nature (2023). She also served as lecturer of the course “'Metabolomics and Drug Discovery' within the II level Master’s program in Drug Design & Synthesis, University of Siena (2023,2025).

 

RESEARCH FIELDS:

NMR-based metabolomics and diseases; cellular effects of (metallo-)drugs; NMR characterization of small molecule-protein interactions; 13C NMR applied to bacterial cultures

 

SELECTED PUBLICATIONS:

1)     Cosottini L*, Geri A*, Ghini V*, Mannelli M, Zineddu S, Di Paco G, Giachetti A, Massai L, Severi M, Gamberi T, Rosato A, Turano P, Messori L. Unlocking the Power of Human Ferritin: Enhanced Drug Delivery of Aurothiomalate in A2780 Ovarian Cancer Cells. Angewandte Chemie International Edition, 2024, e202410791. *equal contribution.
2)     Ghini V*, Meoni G*, Pelagatti L, Celli T, Veneziani F, Petrucci F, Vannucchi V, Bertini L, Luchinat C, Landini G, Turano P. Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients. PLoS Pathog, 2022, 18(4): e1010443. *equal contribution.
3)    Meoni G*, Ghini V*, Maggi L, Vignoli A, Mazzoni A, Salvati L, Capone M, Vanni A, Tenori L, Fontanari P, Lavorini F, Peris A, Bartoloni A, Liotta F, Cosmi L, Luchinat C, Annunziato F, Turano P, Metabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumab. 2021, PLoS Pathog, 17 (2), e1009243. *equal contribution.
4)    Wang Z, Pisano S, Ghini V, Kadeřávek P, Zachrdla M, Pelupessy P, Kazmierczak M, Marquardsen T, Tyburn J-M, Bouvignies G, Parigi G, Luchinat C, Ferrage F. Detection of Metabolite–Protein Interactions in Complex Biological Samples by High-Resolution Relaxometry: Toward Interactomics by NMR. 2021, J Am Chem Soc, 143(25), 9393-9404.
5)    Perrin E*, Ghini V*, Giovannini M, Di Patti F, Cardazzo B, Carraro L, Fagorzi C, Turano P, Fani R, Fondi M. Diauxie and co-utilization of carbon sources can coexist during bacterial growth in nutritionally complex environments. Nat Commun, 2020, 11, 3135-3151. *equal contribution.
6)    Ghini V, Laera L, Fantechi B, Del Monte F, Benelli M, McCarteny A, Tenori L, Luchinat C, Pozzessere D, Metabolomics to assess response to immune checkpoint inhibitors in patients with non-small-cell lung cancer. 2020, Cancers 12 (12), 3574.
7)   Vignoli A*, Ghini V*, Meoni G*, Licari C, Takis P, Tenori L, Turano P, Luchinat C. High-throughput metabolomics by 1d NMR. Angew Chem Int Ed Engl. 2019 ;58(4):968-994. *equal contribution.