Aggregation of α-synuclein (α-syn) is a prominent feature of Parkinson’s disease (PD) and other synucleinopathies. read more

Thanks to recent improvements in NMR spectrometer hardware and pulse sequence design, modern 13C NMR has become a useful tool for biomolecular applications. read more

Fluorinated amino acids can be easily incorporated in proteins expressed in human cells, allowing 19F in-cell NMR studies of proteins that would otherwise be invisible by 1H-detected in-cell NMR. read more

Multispecific biologics are an emerging class of drugs, in which antibodies and/or proteins designed to bind pharmacological targets are covalently linked or expressed as fusion proteins to increase both therapeutic efficacy and safety. read more