Full professor
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AFFILIATION: ADDRESS: CONTACTS: RESEARCH PROFILES: |
Full Professor of Chemistry at the University of Florence, co-founder and former Director of the Center of Magnetic Resonance (CERM), co-founder and present Director and President of the Interuniversity Consortium on Magnetic Resonance of Metallo Proteins (CIRMMP).
RESEARCH FIELDS: Structural Biology, Theoretical developments, metabolomics, relaxometry.
SELECTED PUBLICATIONS: PG Takis, V Ghini, L Tenori, P Turano, C Luchinat Uniqueness of the NMR approach to metabolomics, TrAC Trends in Analytical Chemistry, https://doi.org/10.1016/j.trac.2018.10.036, 2019. Li H, Parigi G, Luchinat C, Meade TJ. Bimodal Fluorescence-Magnetic Resonance Contrast Agent for Apoptosis Imaging, J.Am.Chem.Soc., 2019 doi: 10.1021/jacs.8b13376. Vignoli A, Tenori L, Giusti B, Takis PG, Valente S, Carrabba N, Balzi D, Barchielli A, Marchionni N, Gensini GF, Marcucci R, Luchinat C, Gori AM. NMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort, BMC Med., 17, 3, 2019. Vignoli A, Ghini V, Meoni G, Licari C, Takis PG, Tenori L, Turano P, Luchinat C. High-Throughput Metabolomics by 1D NMR, Angew.Chem.Int.Ed., 58, 968-994, 2019. N. Rezaei-Ghaleh, G. Parigi, A. Soranno, A. Holla, S. Becker, B. Schuler, C. Luchinat, M. Zweckstetter, Local and Global Dynamics in Intrinsically Disordered Synuclein, Angew.Chem.Int.Ed., 57, 15262-15266, 2018. Rumpel S, Ravera E, Sommer C, Reijerse E, Farès C, Luchinat C, Lubitz W, 1H NMR Spectroscopy of [FeFe] Hydrogenase: Insight into the Electronic Structure of the Active Site, J.Am.Chem.Soc., 140, 131-134, 2018. McCartney A, Vignoli A, Biganzoli L, Love R, Tenori L, Luchinat C, Di Leo A Metabolomics in breast cancer: A decade in review, Cancer Treat.Rev., 67, 88-96, 2018. Bellomo G, Bologna S, Gonnelli L, Ravera E, Fragai M, Lelli M, Luchinat C. Aggregation kinetics of the Aβ1-40 peptide monitored by NMR, Chem.Commun. (Camb), 7601-7604, 2018. Liu, G., Levien, M., Karschin, N., Parigi, G., Luchinat, C., and Bennati, M., One-thousand fold enhancement of high field liquid nuclear-magnetic resonance signals at room temperature, Nat.Chem., 9, 676-680, 2017. Takis, PG; Schaefer,H.; Spraul, M.; Luchinat,C.; Deconvoluting interrelationships between concentrations and chemical shifts in urine provides a powerful analysis tool, Nat.Comm., 8, 1662, 2017. Giuntini, S., Balducci, E., Cerofolini, L., Ravera, E., Fragai, M., and Berti, F., Luchinat,C., Characterization of conjugation pattern in large polysaccaride-protein conjugates by NMR, Angew.Chem.Int.Ed., 56, 14997-15001, 2017. Lal, P., Cerofolini, L., D'Agostino, VG, Zucal, C., Fuccio, C., Bonomo, I, Dassi, E., Giuntini, S., Di Maio, D., Vishwakarma, V., Preet, R., Williams, SN, Fairlamb, MS, Munk, R, Lehrmann, E, Abdelmohsen, K, Elezgarai, SR, Luchinat, C., Novellino, E., Quattrone, A., Biasini, E, Manzoni, L, Gorospe, M, Dixon, DA, Seneci, P, Marinelli, L., Fragai, M., and Provenzani, A., Regulation of HuR structure and function by dihydrotanshione-I, Nucleic Acids Res., 45, 9514–9527, 2017. Andralojc, W., Hiruma, Y., Liu, W.-M., Ravera, E., Nojiri, M., Parigi, G., Luchinat, C., and Ubbink, M., Identification of productive and futile encounters in an electron transfer protein complex, Proc.Natl.Acad.Sci.USA, 114, E1840-E1847, 2017. Rammohan, N., MacRenaris, K. W., Moore, L., Parigi, G., Mastarone, D. J., Manus, L. M., Lilley, L., Preslar, A., Waters, E. A., Filicko, A., Luchinat, C., Ho, D. and Meade, T.J., Nanodimond-gadolinium(III) aggregates for tracking cancer growth in vivo at high field, Nano Letters, 16: 7551–7564, 2016. Carlon, A., Ravera, E., Hennig, J., Parigi, G., Sattler, M. and Luchinat, C., Improved accuracy from joint X-ray and NMR refinement of a protein-RNA complex structure, J.Am.Chem.Soc., 138: 1601-1610, 2016. Ravera, E., Ciambellotti, S., Cerofolini, L., Martelli, T., Kozyreva, T., Bernacchioni, C., Giuntini, S., Fragai, M., Turano, P. and Luchinat, C., Solid-state NMR of PEGylated proteins, Angew.Chem.Int.Ed., 55: 1-5, 2016. Benda, L., Mareš, J., Ravera, E., Parigi, G., Luchinat, C., Kaupp, M., and Vaara, J., Pseudo-contact NMR shifts over a paramagnetic metalloprotein (CoMMP-12) from first principles, Angew.Chem.Int.Ed., 55, 14713-14717, 2016. |