Aggregation of α-synuclein (α-syn) is a prominent feature of Parkinson’s disease (PD) and other synucleinopathies. read more

Intrinsically disordered proteins are abundant in eukaryotic systems, but they remain largely elusive pharmacological targets. NMR spectroscopy proved to be a suitable method to study these proteins. read more

Fluorinated amino acids can be easily incorporated in proteins expressed in human cells, allowing 19F in-cell NMR studies of proteins that would otherwise be invisible by 1H-detected in-cell NMR. read more

An effective delivery system is crucial for ensuring the therapeutic efficacy of a drug. This is especially true for biological drugs, which possess unique physicochemical properties and complex pharmacokinetic profiles, and thus require a dedicated design. read more