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Isabella C. Felli graduated with a degree in Chemistry in 1994 and obtained the PhD in Chemistry in 1998 at the University of Florence (Italy) under the supervision of Prof. Bertini. She joined the group of Prof. Bodenhausen as visiting student at the NHMFL in Tallahassee. She received an Alexander von Humbold fellowship for a post-doctoral position in Frankfurt with Prof. Griesinger. She then returned to Florence in the group of Prof. Bertini.
Since 2005 she is associate professor at the University of Florence. She is a member of the Supervisory Board of the Doctorate in Chemistry (Faculty of Science) and of the International Doctorate in Structural Biology (Faculty of Science).
She is involved in the following EC FP7 projects:
Her main research interest consists in the application and development of NMR methods to study biological systems.
Teaching Activity
AA 2006/2007 – now
NMR Spectroscopy(6 CFU) – Faculty of Science, Chemistry
The aim of the course is to provide the basic knowledge to have structural and dynamic information on molecules. The main technique is NMR spectroscopy (NMR). The course is made up of different modules: introduction, product operator formalism, bulding blocks constituting NMR experiments, ``tips and tricks'' to optimize experimental set-up, the instrumentation, the spins beyond protons. The course is constituted by lectures and practicals in front of advanced instrumentation.
AA 2005/2006 – now
Inorganic Structural Genomics - Module B (3 CFU) – Faculty of Science, Chemistry of Biological Molecules
Inorganic structural genomics consists in the characterization of all the 3D structures of proteins that interact with metal ions encoded in the genome. The “structural genomics” approach, a consequence of genome sequencing projects, stimulated a systematic, global analysis of protein structures that allows us to have information on the types of fold, the driving forces that determine the folding process and the network of interactions between proteins.
AA 2003/2004 – now
Improving the NMR Culture (6 CFU) – International Doctorate in Structural Biology.
For the program of the course please click here
Previous:
AA 2001/2002 – 2002/2008
Food Chemistry (Coordination, 6 CFU, Teaching 2 CFU) – Faculty of Science, Applied Chemistry
The course is constituted by 4 modules, two of which held by external experts. 1) The molecules: macronutrients (proteins, lipids and carbohydrates), micronutrients (vitamins, minerals). 2) Different kinds of food, 3) Degradation and conservation; 4) Spectroscopic techniques to control food and toxic metal ions and some recent problematics (BSE, OGM).
Links
Databases
GenBank - http://www.ncbi.nlm.nih.gov/Genebank/
EMBL nucleotide sequence database - http://www.ebi.ac.uk/embl
DNA Database of Japan - http://www.ddbj.nig.ac.jp/
Sanger Institute - http://www.sanger.ac.uk/DataSearch/
ExPASy Proteomics Server - http://www.expasy.ch/
SWISSPROT - http://www.expasy.ch/prot/
Sequence Retrieval System - http://www.expasy.org/srs5/
PROSITE - http://us.expasy.org/prosite/
Genomes - http://www.ncbi.nih.gov/Genomes/
TIGR - http://www.tigr.org/tdb/
BLAST, PSI-BLAST - http://www.ncbi.nlm.nih.gov/BLAST
InterPro - http://www.ebi.ac.uk/interpro
Modeler - http://salilab.org/modeller/
Pfam - http://pfam.wustl.edu/
CATH - http://www.biochem.ucl.ac.uk/bsm/cath/cath.html
SCOP - http://scop.mrc-lmb.cam.ac.uk/scop/
FSSP - http://swift.cmbi.kun.nl/swift/fssp/
TargetDB - http://targetdb.pdb.org
DALI - http://www.ebi.ac.uk/dali/
Validation
PROCHECK - http://www.biochem.ucl.ac.uk/~roman/procheck/procheck.html
PROCHECK-NMR - http://www.biochem.ucl.ac.uk/~roman/procheck_nmr/procheck_nmr.html
AQUA - http://tang.bmrb.wisc.edu/~jurgen/aqua/
WHAT IF - http://swift.cmbi.kun.nl/whatif/
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