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Dr. Giacomo Parigi E-mail: parigi |
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Giacomo Parigi was born in 1967, degree in Physics cum laude at the University of Florence(1992) and PhD in Chemistry at the University of Florence. Postdoctor, Researcher (1999-2006) and associate professor of Chemistry (2006-) at CERM and Faculty of Agricultural Sciences, University of Florence. His research interests include nuclear and electron relaxation, paramagnetism-based effects in NMR, bioinformatics for structure calculations. He is co-author of the book "Solution NMR of Paramagnetic Molecules" with I. Bertini and C. Luchinat
Selected recent publicationsI. Bertini, C. Luchinat, G. Parigi, “Moving the frontiers in solution and solid state bioNMR”, Coord. Chem. Rev. (2011) 255, 649-663. D.J. Mastarone, V.S.R. Harrison, A.L. Eckermann, G. Parigi, C. Luchinat, T.J. Meade, “A Modular System for the Synthesis of Multiplexed Magnetic Resonance Probes”, J. Am. Chem. Soc. (2011) 133, 5329-5337. I. Bertini, C. Luchinat, G. Parigi, E. Ravera, B. Reif, P. Turano, “Solid State NMR of proteins sedimented by ultracentrifugation”, Proc. Natl. Acad. Sci. USA (2011) 108, 10396-10399. I. Bertini, A. Giachetti, C. Luchinat, G. Parigi, R. Pierattelli, E. Ravera, M.V. Petoukhov, D.I. Svergun, “Conformational space of flexible biological macromolecules from average data”, J. Am. Chem. Soc. (2010) 132, 13553–13558. I. Bertini, P. Kursula, C. Luchinat, G. Parigi, J. Vahokoski, M. Wilmanns, J. Yuan, “Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples”, J. Am. Chem. Soc. (2009) 131, 5134–5144. P. Höfer, G. Parigi, C. Luchinat, P. Carl, G. Guthausen, M. Reese, T. Carlomagno, C. Griesinger, M. Bennati, “Field Dependent Dynamic Nuclear Polarization with Radicals in Aqueous Solution”, J. Am. Chem. Soc. (2008) 130, 3254-3255. C. Luchinat, G. Parigi, “Collective relaxation of protein protons at very low magnetic field: a new window on protein dynamics and aggregation”, J. Am. Chem. Soc. (2007) 129, 1055-1064. I. Bertini, Y.K. Gupta, C. Luchinat, G. Parigi, M. Peana, L. Sgheri, J. Yuan, “Paramagnetism-based NMR restraints provide maximum allowed probabilities for the different conformations of partially independent protein domains”, J. Am. Chem. Soc. (2007) 129, 12786-12794. J.L. Major, G. Parigi, C. Luchinat, T.J. Meade, “The synthesis and in vitro testing of a zinc-activated MRI contrast agent”, Proc. Natl. Acad. Sci. USA (2007) 104, 13881-13886. M. Fragai, C. Luchinat, G. Parigi, “Four dimensional protein structures: examples from metalloproteins”, Acc. Chem. Res. (2006) 39, 909-917. I. Bertini, C. Luchinat, G. Parigi, “1H NMRD profiles of paramagnetic aquo-complexes and metalloproteins”, Adv. Inorg. Chem. (2005) 57, 105-172. In R. van Eldik and I. Bertini, “Relaxometry of water-metal ion interactions”. I. Bertini, Y.K. Gupta, C. Luchinat, G. Parigi, C. Schlörb, H. Schwalbe, “NMR Spectroscopic Detection of Protein Protons and Longitudinal Relaxation Rates between 0.01 and 50 MHz”, Angewandte Chemie Int. Ed. (2005) 44, 2-4. I. Bertini, C. Del Bianco, I. Gelis, N. Katsaros, C. Luchinat, G. Parigi, M. Peana, A. Provenzani, M.A. Zoroddu, “Experimentally exploring the conformational space sampled by domain reorientation in calmodulin”, Proc. Natl. Acad. Sci. USA (2004) 101, 6841-6846
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